Biomarkers, screening, standardized and non-standardized ecotoxicological testing in One Health drug discovery and development

Second workshop WG4, Gießen (in presence),

Abstract

“Biomarkers, screening, standardized and non-standardized ecotoxicological testing in One Health drug discovery and development”

In the development of new active substances, consideration of possible effects on non-target organisms is becoming increasingly important. What is already well established in pesticide development, namely the assessment of environmental effects, is still in its infancy in drug development. Here, the One Health approach often still falls short, as environmental health is an integral part of this concept, in addition to animal and human health. Efficient, innovative but also standardizable test methods and assays are needed to assess the behavior and effects of active ingredients released into the natural environment. The second workshop of WG4 will provide a platform to present and discuss different assays and test methods. Initial results of WG1-3 will be summarized and evaluated in an integrative manner with the goal of proposing a guideline paper to address ecotoxicological concerns in drug discovery and development in the anti-parasitic field. Visits to two research facilities focusing on drug discovery from bioresources or on risk assessment up to the mesocosm or field scale will round out the workshop.

For questions, contact the meeting organizer: Rolf-Alexander Düring, rolf-alexander.duering@umwelt.uni-giessen.de

If interested in participating in presence, please register at the following link:

https://docs.google.com/forms/d/e/1FAIpQLSeuamqceQhC4PU3uGjgEljD1eOUgjR81mXamuQtJWNsTg_zLw/viewform?usp=sharin