1. Current Treatments to Control African Trypanosomiasis and One Health Perspective. 

By: Venturelli A, Tagliazucchi L, Lima C, Venuti F, 
Malpezzi G, Magoulas GE, Santarem N, Calogeropoulou T, Cordeiro-da-Silva A and Costi MP Microorganisms. 2022 Jun 27;10(7):1298. DOI: 10.3390/microorganisms10071298.

2. Comparison of Bioluminescent Substrates in Natural Infection Models of Neglected Parasitic Diseases

By: Hendrickx S, Bulté D, Mabille D, Mols R, Claes M, Ilbeigi K, Ahmad R, Dirkx L, Van Acker SI and Caljon G
Int. J. Mol. Sci. 2022, 23(24), 16074; DOI: 10.3390/ijms232416074

 

3. Impact of pulmonary African trypanosomes on the immunology and function of the lung

By: Mabille D, Dirkx L, Thys S, Vermeersch M, Montenye D, Govaerts M, Hendrickx S, Takac P, Van Weyenbergh J, Pintelon I, Delputte P, Maes L, Pérez-Morga D, Timmermans J-P and Caljon G. Nat Commun 13, 7083 (2022), DOI: 10.1038/s41467-022-34757-w

 

4. Label-Free Mass Spectrometry Proteomics Reveals Different Pathways Modulated in THP-1 Cells Infected with Therapeutic Failure and Drug Resistance Leishmania infantum Clinical Isolates. 

By: Tagliazucchi L, Perea-Martinez A, Fiorini G, Manzano JI, Genovese F, García-Hernández R, Pinetti D, Gamarro F and Costi MP ACS Infect Dis. 2023 Mar 10;9(3), DOI: 10.1021/acsinfecdis.2c00457. 

 

5. Cloning and Characterization of Trypanosoma congolense and T.Vivax Nucleoside Transporters Reveal the Potential of P1-Type Carriers for

the Discovery of Broad-Spectrum Nucleoside-Based Therapeutics against Animal African Trypanosomiasis.

Ungogo MA, Aldfer MM, Natto MJ, Zhuang H, Chisholm R, Walsh K, McGee M, Ilbeigi K, Asseri JI, Burchmore RJS, Caljon G, Van Calenbergh S, De Koning HP.

Int J Mol Sci. 2023 Feb 5;24(4):3144. doi:10.3390/ijms24043144. PMID: 36834557; PMCID: PMC9960827.

 

6. Target or Not to Target Schistosoma mansoni Cyclic Nucleotide Phosphodiesterase 4A

 Zheng Y, Schroeder S, Kanev GK, Botros SS, William S, Sabra AA, Maes L, Caljon G, Gil C, Martinez A, Salado IG, Augustyns K, Edink E, Sijm M, de Heuvel

E, de Esch IJP, van der Meer T, Siderius M, Sterk GJ, Brown D, Leurs R. Int J Mol Sci. 2023 Apr 6;24(7):6817. doi: 10.3390/ijms24076817. PMID: 37047792; PMCID: PMC10095301.

 

7. 2-Aroyl quinazolinone: Synthesis and in vitro anti-parasitic activity.

Setshedi KJ, Beteck RM, Jesumoroti OJ, Ilbeigi K, Mabille D, Caljon G, Van der Kooy F, Legoabe LJ. Chem Biol Drug Des. 2023 Jun 23. doi: 10.1111/cbdd.14284.

Epub ahead of print. PMID: 37353860.

 

8. Optimization of BIPPO Analogs as Potent Antimalarials

Zheng Y, Matheeussen A, Maes L, Caljon G, Sterk GJ, Leurs R. Structural. 2023 Jun. 23;28(13):4939. doi: 10.3390/molecules28134939. PMID: 37446602; PMCID:

PMC10343887.

 

 

COST
What is COST?

COST (European Cooperation in Science and Technology) is a funding agency for research and innovation networks. The COST ACTIONS help connect research initiatives across Europe and enable scientists to grow their ideas by sharing them with their peers. This boosts their research, career and innovation.

OneHealthdrugs CA21111
Title:

One Health drugs against parasitic vector borne diseases in Europe and beyond

Acronym:

OneHealthdrugs

Start date of the Action:

24/10/2022

End date of the Action:

23/10/2026

CSO approval date:

27/05/2022

Memorandum of Understanding (MoU)

Download file

Contact Points
Chair:

Maria Paola Costi

Vice-Chair:

Anabela Cordeiro da Silva

COST staff

Scientific Officer:
Lucia Forzi
Administrative Officer:
Nathalie Warenghien

Administrative Team

Maria Cristina Notarsanto
Maria Esposito and Laura Leonardi